• Publications
  • 2025

RNA interference in vivo: toward synthetic small inhibitory RNA-based therapeutics

Methods Enzymol. 2005;392:278-96

  • siRNA
  • RNA chemistry & modifications
  • Publications
  • 2025

Effective silencing of EGFR with RNAi demonstrates non-EGFR dependent proliferation of glioma cells

Int J Oncol

  • siRNA
  • RNA chemistry & modifications
  • Molecular & cellular biology
  • Posters
  • 2025

mRNA CQA Analysis from 5' to 3'-End

PDF document.

  • Publications
  • 2024

Conformation matters: siRNAs with antisense strands with 5'-(E)-vinyl-phosphonate-∝-L-LNA elicit stronger RNAi-mediated gene silencing than those with 5'-(E)-vinyl-phosphonate-LNA

  • siRNA
  • RNA chemistry & modifications
  • Molecular & cellular biology
  • Posters
  • 2024

Comparison of two Bioanalytical Assays - PNA-HPLC-Assay and LC-MS/MS-Assay

PDF document.

  • Posters
  • 2024

RNA-seq-based Nucleic Acid Therapeutics Lead Optimization

PDF document.

  • Posters
  • 2024

Discovery of a Novel C3-Targeting and CNS Active siRNA as a Potential Therapeutic for Alzheimer's Disease

PDF document.

  • Publications
  • 2024

The Tautomeric State of N4-Hydroxycytidine within Base-Paired RNA

  • RNA chemistry & modifications
  • Posters
  • 2024

Investigating the Impact of Linear Flow Rate on Purification Performance

PDF document.

  • Publications
  • 2024

Illuminating Neuropeptide Y Y4 Receptor Binding: Fluorescent Cyclic Peptides with Subnanomolar Binding Affinity as Novel Molecular Tools

  • Molecular & cellular biology
  • Publications
  • 2024

Atomic Mutagenesis of N6-Methyladenosine Reveals Distinct Recognition Modes by Human m6A Reader and Eraser Proteins. Seitz F

  • Molecular & cellular biology
  • Drug delivery & bioanalytics
  • Posters
  • 2024

Reaction condition optimization to minimize hydrolysate formation in a maleimide-NHS esteroligonucleotide conjugation reaction

PDF document.

  • Posters
  • 2023

Auto MS/MS and targeted MS/MS in-depth qualitative and quantitative analysis of oligonucleotide synthesis products and side products

PDF document.

  • Publications
  • 2023

Lipid nanoparticle-encapsulated, chemically modified anti-adenoviral siRNAs inhibit hepatic adenovirus infection in immunosuppressed Syrian hamsters

  • siRNA
  • RNA chemistry & modifications
  • Molecular & cellular biology
  • Drug delivery & bioanalytics
  • Posters
  • 2023

An alternative desilylation condition using NH4F

PDF document.